Sökning: "histone"
Visar resultat 1 - 5 av 23 uppsatser innehållade ordet histone.
1. The Quantitative Expression of Transport Proteins SLC38A1-11 in Nerve Cell Development
Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskapSammanfattning : Solute carriers consist of over 400 genes and 66 subfamilies and are the largest group of membrane bound transporters. They facilitate movement of many molecules through cells and organelles and are crucial for upholding many key functions in the human body. They are also involved in the pathophysiology of several diseases. LÄS MER
2. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles
Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisationSammanfattning : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. LÄS MER
3. Epigenetic and transcriptional effects of full-length LINE-1 retrotransposons in human neural progenitor cells
Master-uppsats, Lunds universitet/Examensarbeten i bioinformatikSammanfattning : Transposable elements (TE) are parasitic genetic entities that have the ability to alter their position within a genome and have the potential to influence its functionality. Although TEs play beneficial roles in the evolution of their host, they are active in various human disorders including neurological diseases, where may contribute to the progress of the disease. LÄS MER
4. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia
Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. LÄS MER
5. Histone modifications and their role in splicing
Kandidat-uppsats, Linköpings universitet/BiologiSammanfattning : Splicing is the process when introns gets removed and exons are spliced together. This is an important step to form a clean mRNA with no unnecessary sequences that could interrupt protein synthesis. There are different types of splicing and some of them need a complex called spliceosome. LÄS MER