Sökning: "in vitro dissolution"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden in vitro dissolution.

  1. 1. The optimization of a manual dissolution method and its equivalence to automated dissolution

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk farmaceutisk kemi

    Författare :Diana Cicek; [2022]
    Nyckelord :;

    Sammanfattning : In vitro dissolution assays are used to study how a pharmaceutical formulation will behave in vivo. The assay is performed to estimate how the API of the dosage form is released in the body after administration. LÄS MER

  3. 2. In vitro study of Biodegradation in Mg-alloys by Isothermal Calorimetry

    Master-uppsats, Lunds universitet/Industriell Produktion

    Författare :Prasad Rajendra Kekare; Akshat Kulkarni; [2021]
    Nyckelord :Isothermal Calorimetry; Degradation of Mg Alloys; Supersaturated solid solution SSSS ; Corrosion rate; Aqueous corrosion.; Technology and Engineering;

    Sammanfattning : Magnesium corrosion in an aqueous environment is a multi-layer, complex process. A literature survey shows significant gaps and the modelling work reported indicates a lack of clarity in understanding the corrosion process. LÄS MER

  4. 3. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Venus Zafranian; [2021]
    Nyckelord :Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

    Sammanfattning : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. LÄS MER

  5. 4. Characterization of the effect of the membrane on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Maral Simonides; [2021]
    Nyckelord :Oral inhalation; in vitro dissolution; Budesonide; Fluticasone propionate; Transwell;

    Sammanfattning : It has always been a challenge to imitate the lung environment, therefore there is a constant development of standardized in vitro dissolution methods for inhaled products. Dissolution in vitro has been considered as an important parameter, because low solubility determines the bioavailability of inhaled drugs. LÄS MER

  7. 5. Using Upsalite® as drug delivery vehicle : Increasing the solubility of poorly soluble drugs by stabilizing their amorphous state

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Ottilia Arvén; [2017]
    Nyckelord :;

    Sammanfattning : Poor aqueous solubility is an issue not only in drug discovery and development but also for registered drug products, since poor drug solubility is often related to poor absorption (bioavailability). There are several methods available to increase the aqueous solubility and dissolution rate of pharmaceutical formulations. LÄS MER