Sökning: "pulmonary drug delivery"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden pulmonary drug delivery.

  1. 1. DRY POWDER FOR INHALATION - INFLUENCE OF MIXING PROCESS AND ADDITION OF MAGNESIUM STEARATE

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Love Ivarsson; [2023]
    Nyckelord :inhalation; drug delivery; pulmonary drug delivery; API; FPF; FPD; DD; Turbula; Diosna; mixing energy; mixing time; mixing speed; pharmaceutical technology; Medicine and Health Sciences;

    Sammanfattning : For efficient treatment of many diseases of the lung, it is beneficial to deliver the medicine to the respiratory tract directly. This ensures a rapid response since it can enter the bloodstream directly through the alveolar epithelium. Consequently, also decreases systemic effects due to the local treatment. LÄS MER

  3. 2. Hur förhåller sig Region Uppsalas klimatavtryck från inhalatorer till andra regioner?

    Kandidat-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Vincent Kreidy; [2022]
    Nyckelord :inhalatorer; sprayinhalatorer; drivgas; astma; miljö; miljöbelastning; flourkolväte; HFC; Norfluran; Apafluran; Uppsala; Klimat; miljö;

    Sammanfattning : Background: Pressurized metered dose inhalers (pMDI) use propellants for pulmonary drug delivery. The propellants used in pMDI:s are strong greenhouse gases. The Powder dose inhaler (PDI) doesn’t use any propellants and contributes less to the carbon footprint. LÄS MER

  4. 3. Adhesive mixtures for dry powder inhalation

    Magister-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Louise Lagercrantz Forss; [2021]
    Nyckelord :Adhesive mixtures; dry powder inhaler; excipients; pulmonary route; powder mixing;

    Sammanfattning : When it comes to dry powder inhalation (DPI), adhesive mixtures are the most widely used formulation type. Various techniques have been developed to generate inhaled drug particles and improve the delivery efficiency of DPI formulations. LÄS MER

  5. 4. The influence of dissolution medium on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Venus Zafranian; [2021]
    Nyckelord :Inhalation; in vitro dissolution; budesonide; fluticasone propionate; modified andersen cascade impactor; pulmonary drug delivery; dissolution profiles; dissolution medium;

    Sammanfattning : Today, orally inhaled drugs found on the market suffer from variable and discontinuous pulmonary drug release which lowers efficacy and patience compliance. This is usually a consequence of the poor understanding of the interaction and dissolution behavior of drug particles in the lung environment. LÄS MER

  7. 5. Characterization of the effect of the membrane on in vitro dissolution profiles for pulmonary drug delivery

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

    Författare :Maral Simonides; [2021]
    Nyckelord :Oral inhalation; in vitro dissolution; Budesonide; Fluticasone propionate; Transwell;

    Sammanfattning : It has always been a challenge to imitate the lung environment, therefore there is a constant development of standardized in vitro dissolution methods for inhaled products. Dissolution in vitro has been considered as an important parameter, because low solubility determines the bioavailability of inhaled drugs. LÄS MER