Sökning: "prolyl hydroxylase"
Hittade 2 uppsatser innehållade orden prolyl hydroxylase.
1. Hypoxia and hematopoietic stem cell control with the substance Adaptaquin : An evaluation of hematopoietic stem cell’s proliferation and differentiation in artificially induced hypoxia
Kandidat-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)Sammanfattning : Hematopoietic stem cells (HSCs) have historically been difficult to maintain ex vivo with many attempts to culture them in vitro by mimicking their natural biological environment. Providing a hypoxic environment is one way to achieve this goal and can be performed by using hypoxia stimulating compounds that inhibits the degradation of HIF1a which plays an important role in regulating hypoxia. LÄS MER
2. Production, in vitro modification, and interaction analysis of a hydroxyproline-dependent protein
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/BiokemiSammanfattning : The development of a biologic protein involves different stages and becomes a highly complex process which can be costly and time consuming to scale up for industrial production. Therefore, optimization is a necessary part of the production process development to lower the production expenses. LÄS MER