Sökning: "Alzahra Hamdan"

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  1. 1. Automatic Development of Pharmacokinetic Structural Models

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Alzahra Hamdan; [2022]
    Nyckelord :pharmacometrics; non-linear mixed effects; modelling; pharmacokinetics; NONMEM; automation; exhaustive algorithm; stepwise algorithm; structural models; inter-individual variability; residual error models; model selection;

    Sammanfattning : Introduction: The current development strategy of population pharmacokinetic models is a complex and iterative process that is manually performed by modellers. Such a strategy is time-demanding, subjective, and dependent on the modellers’ experience. LÄS MER