Sökning: "BOLD amplification"

Hittade 2 uppsatser innehållade orden BOLD amplification.

1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

   Författare :Sam Vadi Dris; [2024]
   Nyckelord :Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

   Sammanfattning : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. LÄS MER

3. 2. Signal amplification in a microfluidic immunoassay system via Binding Oligo Ladder Detection : Applying the Exazym® signal amplification to the Gyrolab® platform

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaci

   Författare :Daniel Wiman; [2023]
   Nyckelord :immunoassay; ultra-sensitive; signal amplification; Gyrolab; Exazym; high sensitivity; microfluidics; BOLD amplification; nucleic acid polymerisation;

   Sammanfattning : Immunoassays are analytical methods that use the highly specific binding of antibodies in order to detect and quantify an analyte. The technique has become a staple in modern biopharmaceutical research and diagnostics, however the measurement of biomarkers like dysregulated cytokines require ultra-sensitive immunoassays that can detect molecules at sub pg/mL concentrations. LÄS MER