Sökning: "GWAS"

Visar resultat 26 - 30 av 33 uppsatser innehållade ordet GWAS.

  1. 26. Mediation modeling and analysis forhigh-throughput omics data

    Master-uppsats, Uppsala universitet/Statistiska institutionen

    Författare :Ning Zheng; [2015]
    Nyckelord :Mediation model; metabolite; SNP; BMI;

    Sammanfattning : There is a strong need for powerful unified statistical methods for discovering underlying genetic architecture of complex traits with the assistance of omics information. In this paper, two methods aiming to detect novel association between the human genome and complex traits using intermediate omics data are developed based on statistical mediation modeling. LÄS MER

  3. 27. Tollarsjuka : resultat av ett naturligt urval?

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Lovisa Hällström; [2015]
    Nyckelord :autoimmunitet; Tollarsjuka; IMRD; SRMA; DLA klass II; autoimmunity; DLA class II;

    Sammanfattning : Hundrasen Nova Scotia Duck Tolling Retriever (Tollare), en apporterande ras med ursprung i Kanada, var i början på 1900-talet nära att utrotas på grund av två epidemier av valpsjuka som härjade i landet. I dag har rasen rapporterats vara predisponerad för vissa immunmedierade sjukdomar däribland s.k. tollarsjuka. LÄS MER

  4. 28. Gene-EnvironmentInteraction Analysis UsingGraphic Cards

    Master-uppsats, KTH/High Performance Computing and Visualization (HPCViz)

    Författare :Daniel Berglund; [2015]
    Nyckelord :HPC; high performance computing; CUDA; GPU; GWAS; gene-environment interaction; interaction;

    Sammanfattning : Genome-wide association studies(GWAS) are used to find associations betweengenetic markers and diseases. One part of GWAS is to study interactions be-tween markers which can play an important role in the risk for the disease. Thesearch for interactions can be computationally intensive. LÄS MER

  5. 29. Genome wide association study of milk composition traits in Swedish Red cows

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Yohannes Goitom Tesfayonas; [2014]
    Nyckelord :Milk composition; single nucleotide polymorphism SNP ; GWAS;

    Sammanfattning : The aim of this study was to detect QTLs that affect milk composition traits such as fat yield, fat percent, citric acid, free fatty acids as well as milk properties like fat globule size, and determine the phenotypic variation explained by the QTLs. These traits play a crucial role in nutritional and technological properties of milk and its products. LÄS MER

  7. 30. Genomic analysis of hydrocephalus in Friesian horses

    Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

    Författare :Astri Olivia Herlino; [2013]
    Nyckelord :Friesian horses; genomic analysís; hydrocephalus;

    Sammanfattning : Hydrocephalus is an uncommon disorder in horses. However, hydrocephalus is observed more often in the Friesian horse breed than in other breeds. Due to the Friesian horse population has been closed for outside breeding and has a limited genetic pool. It leads to high rate of inbreeding. LÄS MER