Sökning: "Microglia"

Visar resultat 1 - 5 av 10 uppsatser innehållade ordet Microglia.

  1. 1. Computational prediction of cell-cell interactions in the brain-tumour microenvironment

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Paula Camargo Romera; [2023]
    Nyckelord :Cancer; Glioblastoma; Computational Biology; Bioinformatics; Microenvironment; Brain tumour; Interactions; Systems Biology;

    Sammanfattning : Glioblastoma is the fastest-growing, and the most common malignant brain tumour in adults. It is normally treated with surgery and radio- or chemotherapy, but the approximate life expectancy is of 15 months with a high probability of cancer recurring. Therefore, there is a need for decreasing its severity. LÄS MER

  3. 2. Characterization of the immunomicroenvironment of glioblastoma : Optimization of an antibody panel for detection of glioblastoma TME cells and effect of C3 on glioma cells.

    Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Författare :Julia Wahldén; [2023]
    Nyckelord :Brain; cancer; glioblastoma; immune cells; immunofluorescence; tumor microenvironment; Cancer; glioblastom; immunceller; immunofluorescens; hjärnan; tumörmikromiljö;

    Sammanfattning : Glioblastoma (GBM) is the most common primary brain tumor in adults and represents one of the most aggressive tumor types. Despite treatment GBM remains incurable and when treated the tumor recurs more aggressive and treatment resistant than before. LÄS MER

  4. 3. A Single-Nucleus RNA Sequencing Analysis of HERVs and LINE1s in Alzheimer's and Parkinson's Disease

    Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

    Författare :Stein Acker; [2022]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Transposable elements (TEs) are mobile genetic elements that make up roughly 50% of the human genome, with retrotransposons (or transposons which retrotranspose via an RNA intermediate) making up the vast majority of these elements. Recent studies have suggested that TEs could play a role in many neurological conditions, including ALS and dementia. LÄS MER

  5. 4. The effects of spinal implant wear debris particles

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Tillämpad materialvetenskap

    Författare :Cecilia Thomas; Eslam El Ammarin; [2021]
    Nyckelord :spine; implant; wear; debris; particles; ryggimplantat; implantatpartiklar; partiklar; implantat;

    Sammanfattning : The goal of this literature study was to study the effects of spinal implant wear debris particles on the body in general, and on microglia cells in particular. The method of the literature study was searching for scientific peer-reviewed papers on the topic.  Spinal implants are used to fix spinal problems such as deformities or injuries. LÄS MER

  7. 5. Differential Thyroid Hormone Signaling in Human Astrocytes and Microglia

    Uppsats för yrkesexamina på avancerad nivå, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Renée Levisson; [2021]
    Nyckelord :Thyroid hormones; Signaling; Astrocytes; Microglia;

    Sammanfattning : Thyroid hormones (THs) play a fundamental role in brain function during development and adulthood. THs are essential regulators of neurogenesis, cell maturation and migration as well myelination and synaptogenesis. LÄS MER