Sökning: "Secretion systems"

Visar resultat 1 - 5 av 14 uppsatser innehållade orden Secretion systems.

  1. 1. Is the Expression of Hemolysin Co-regulated Protein (Hcp) Associated with Serum Resistance in Aggregatibacter aphrophilus?

    Master-uppsats, Umeå universitet/Tandläkarutbildning

    Författare :Clara Settlin; Selva Hot; [2023]
    Nyckelord :Aggregatibacter aphrophilus; hcp; T6SS; serum resistance;

    Sammanfattning : Abstract  Aggregatibacter aphrophilus, a Gram negative bacterium, found in the oral cavity, causing cerebral abscesses and infective endocarditis, has been shown to be serum resistant in previous studies. Bacterial secretion systems are important for bacteria as they transfer virulence factors into other bacteria or host cells as an attack. A. LÄS MER

  3. 2. Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

    Magister-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Fredrik Bertilsson; [2022]
    Nyckelord :Biophysics; systems biology; gene regulatory networks; neural tube; isthmic organizer; midbrain-hindbrain boundary; WNT; FGF; morphogens; reaction-diffusion; finite-difference; 3D modelling; Physics and Astronomy;

    Sammanfattning : Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. LÄS MER

  4. 3. Aspects of Stress-related Health Problems Among Young People in China --the Perspective of Community Health Professionals

    Master-uppsats, Linnéuniversitetet/Institutionen för hälso- och vårdvetenskap (HV)

    Författare :Yueping Wu; [2021]
    Nyckelord :Stress; Health problems; Young people; The PNEI model;

    Sammanfattning : China's modernization process is in a stage of rapid development. With the improvement of the education level of young people, their expectations on their study, career, and living standards are also being high-stress level. The various health problems are increasing among young people who may be experienced high-level stress. LÄS MER

  5. 4. Phylogenetic analysis of secretion systems in Francisellaceae and Legionellales : Investigating events of intracellularization

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Karl Nyrén; [2021]
    Nyckelord :Metagenomics; Phylogenetics; Secretion systems; Francisellaceae; Legionellales; Host-adaptation; Evolution; Intacellularization;

    Sammanfattning : Host-adapted bacteria are pathogens that, through evolutionary time and host-adaptive events, acquired the ability to manipulate hosts into assisting their own reproduction and spread. Through these host-adaptive events, free-living pathogens may be rendered unable to reproduce without their host, which is an irreversible step in evolution. LÄS MER

  7. 5. Optimizing signal peptides for expression of recombinant antibodies in HEK293 cells

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Gustav Myhrinder; [2020]
    Nyckelord :Signal peptide; antibody; mammalian cell; HEK293; secretory pathway;

    Sammanfattning : Monoclonal antibodies are well-established as a therapeutic in the biopharmaceutical market, targeting a variety of diseases and with 79 approved products by the United States Food and Drug Administration in December 2019. Therapeutic monoclonal antibodies are commonly produced as recombinant proteins in mammalian cell lines, due to their capacity of post-translational modifications, most notably glycosylation. LÄS MER