Sökning: "Targeted detection"

Visar resultat 16 - 20 av 68 uppsatser innehållade orden Targeted detection.

  1. 16. Method development and screening of extractable organofluorine (EOF) and targeted PFAS analysis in food packaging materials

    Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Nora Larsson; [2022]
    Nyckelord :Per- and polyfluoroalkyl substances PFAS ; Food packaging materials; Extractable organofluorine; Method development; Combustion ion chromatography; Targeted analysis;

    Sammanfattning : Per- and polyfluoroalkyl substances (PFAS) have been manufactured and used in differentapplications for several decades, including food packaging materials. During the last 20 yearsthese compounds have been acknowledged as hazardous for humans and the environment, anddifferent regulations on PFAS have been established on both national and international levels. LÄS MER

  2. 17. Mass Spectrometric Virus Detection with Multiplex Assay

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Sebastian Augustinsson; [2022]
    Nyckelord :Multiplex assay; Binder; Antigen; Cloning; Pull-down assay; Targeted detection; Mass spectrometry;

    Sammanfattning : Syftet med projektet var att utveckla en multiplexanalys för att detektera antigen från SARS-CoV-2, influensa och respiratoriskt syncytial virus genom att använda en masspektrometrisk metod som involverar antigenspecifika bindare. Bindarna klonades, renades och biotinylerades innan de användes i en analys utvecklad genom en målinriktad metod som involverade antigenerna. LÄS MER

  3. 18. Evaluating Blood Biomarker Profiles in Adults with New-onset Seizures using Machine Learning

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Sarah Akel; [2022]
    Nyckelord :Seizure; Seizures; Epilepsy; Neurology; Biomarker; Biomarkers; Blood Biomarkers;

    Sammanfattning : Around 1% of the population worldwide suffer from epilepsy, a condition which is characterized by recurring seizures. The development of reliable biomarkers for both prediction and targeted treatment of seizures is critical, as they can pave the way towards personalized therapy in epilepsy. LÄS MER

  4. 19. Filtering of Clinical NGS Data to Improve Low Allele Frequency Variant Calling

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Tomas Cumlin; [2022]
    Nyckelord :Next-generation sequencing; Variant calling; Clinical sequencing; Substitution error; Cancer sequencing; Error rate; substitution; Somatic mutation;

    Sammanfattning : Massive parallel sequencing (NGS) is useful in detecting and later classifying somatic driver mutations in cancer tumours. False-positive variants occur in the NGS workflow and they may be mistaken for low frequency somatic cancer mutations in a patient sample. LÄS MER

  5. 20. Monitoring illicit drugs of abuse in wastewater from Umeå, Örebro, Örebro University and Örebro University Hospital

    Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Tove Slettvoll; [2022]
    Nyckelord :;

    Sammanfattning : Illicit drugs constitute a class of contaminants whose emissions to the environment has drawn attention due their potent pharmacological and biological activities. The monitoring of illicit drugs in wastewater and surface waters provides a powerful tool to investigate the presence, trends and to estimate the consumption of these psychoactive substances at the community level. LÄS MER