Sökning: "cytotoxic payload"
Hittade 2 uppsatser innehållade orden cytotoxic payload.
1. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/TheranosticsSammanfattning : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. LÄS MER
2. Antibody drug conjugates (ADC) : Current status and mapping of ADC:s in clinical programs
Kandidat-uppsats, Uppsala universitet/Institutionen för teknikvetenskaperSammanfattning : A literature study was performed on a new type of cancer medicine: antibody drug conjugates, or ADCs. These consist of a monoclonal antibody, chemically linked to a cytotoxic agent. What makes them unique is their selective toxicity against cancer cells. LÄS MER