Sökning: "enzyme inhibitor"
Visar resultat 1 - 5 av 21 uppsatser innehållade orden enzyme inhibitor.
1. Ligand-stimulated cleavage of PDGFR-beta
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. LÄS MER
2. Influence of Nrf2 Activators and Keap1 Inhibitors on Antioxidative Phenotypes of THP-1-Derived M1 and M2 macrophages: Therapeutic Potential for Systemic Lupus Erythematosus
Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologiSammanfattning : POPULAR SCIENTIFIC SUMMARY Systemic lupus erythematosus (SLE) is not your average disorder. It behaves like a mischievous troublemaker, wreaking havoc throughout the body, causing inflammation that affects multiple organs. LÄS MER
3. The GSK-3 inhibitor has no effect on production of IL-1β in LPS- and Nigericin-stimulated THP-1 macrophages
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Inflammation is the body's natural defense reaction and is known since ancient times. The inflammation is divided into two main phases, acute and chronic inflammation dependent on the process and cellular mechanisms of the inflammation. LÄS MER
4. Structure-based design of new antiviral substances against the Venezuelan equine encephalitis virus
Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/BeräkningskemiSammanfattning : The Venezuelan equine encephalitis virus (VEEV) is a highly infectious alphavirus responsible for severe outbreaks and epidemics in the Americas. The nonstructural protein 2 (nsP2) cysteine protease plays a fundamental role in the VEEV replication process, and is therefore, an attractive drug target for structure-based drug design using x-ray crystallography. LÄS MER
5. Association of ACE and PAI-1 gene polymorphisms with clinical outcomes of obstructive sleep apnea
Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsovetenskaperSammanfattning : Obstructive sleep apnoea (OSA) is a sleeping disorder leading to complications such as daytime-sleepiness, migraines and snoring and is often associated with coronary artery disease (CAD). Studies have suggested the contribution of genetic factors in aetiology of OSA. LÄS MER