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1. Restricted Region Exact Designs
Kandidat-uppsats, Linköpings universitet/Matematiska institutionenSammanfattning : Problem statement: The D-optimal design is often used in clinical research. In multi-factor clinical experiments it is natural to restrict the experiment's design space so as not to give a patient the combination of several high dose treatments simultaneously. Under such design space restrictions it is unknown what designs are D-optimal. LÄS MER
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