Sökning: "lactose fines"

Hittade 3 uppsatser innehållade orden lactose fines.

  1. 1. The effect of lactose fines, magnesium stearate, choice of mixer and mixing process on the performance of adhesive mixtures for inhalation

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Gabriela Ponce Aparicio; [2023]
    Nyckelord :High shear mixing; low shear mixing; lactose fines; coating agent; budesonide; mixing energy; dry powder inhaler; carrier-based formulations; mixing time; adhesive mixtures; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : Dry powder inhaler (DPI) formulation is a major area of interest since they are employed by the healthcare system to treat relevant chronic diseases like asthma. Previous research has established that the manufacturing process and formulation composition are key for the active pharmaceutical ingredient to reach the lungs and achieve therapeutic effects. LÄS MER

  2. 2. Comparing different methods of measuring particle size for pharmaceutical excipients

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Jiawen Wang; [2022]
    Nyckelord :particle size; comparison; Malvern analysis; Qicpic analysis; Pharmaceutical technology; Technology and Engineering;

    Sammanfattning : In pharmaceutical science, particle size is one of the most fundamental parameters of materials, but different particle-sizing analysis methods lack a uniform standard for measuring irregular particle size, making it difficult to compare the accuracy and applicability of different particle-sizing analysis methods. Experiments on excipients used in pharmaceuticals are carried out in this paper by laser diffraction analysis (Malvern wet and dry), dynamic image analysis (Qicpic), and microscopic methods (Qicpic, SEM, and light microscopy) to determine the applicability and limitations of each method, as well as to clarify their advantages and disadvantages. LÄS MER

  3. 3. Investigation of mixing time and relative concentration effects in adhesive mixtures for drug inhalation

    Master-uppsats, Lunds universitet/Ergonomi och aerosolteknologi

    Författare :Simon Åslund; [2015]
    Nyckelord :Aerosol Drug Inhalation Adhesive mixtures Next Generation Impactor Laser diffraction; Technology and Engineering;

    Sammanfattning : A common approach to treat respiratory diseases is with adhesive powder mixtures. These are dispersed into an aerosol upon inhalation. It has been found that the performance of such mixtures can be improved by adding fine particle lactose, but exactly why is yet to be established. LÄS MER