Sökning: "short tandem repeats"
Hittade 3 uppsatser innehållade orden short tandem repeats.
1. Validation of a Next Generation Sequencing based method for chimerism analysis in clinical practice
Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologiSammanfattning : Hematopoietic stem cell transplantation (HSCT) is used to treat patient with hematological diseases such as leukemia and genetic conditions such as sickle cell anemia. After HSCT the patients are supervised for signs of relapse of disease or rejection of transplanted cells. This is done by using chimerism analysis. LÄS MER
2. Understanding sequence errors in analysis of short tandem repeats through optimisation of a library preparation protocol utilising unique molecular indices
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : In the last few years massively parallel sequencing (MPS) has become important for forensic DNA analysis by providing new and broader possibilities, such as increased discrimination power for short tandem repeat (STR) analyses. An imperative part of MPS analysis is library preparation where there is a fundamental reliability on in vitro DNA polymerisation, which is prone to errors. LÄS MER
3. Library construction optimization and analysis of Short Tandem Repeats by a simple, PCR-based DNA barcoding method
Master-uppsats, Lunds universitet/Teknisk mikrobiologi; Lunds universitet/BioteknikSammanfattning : DNA profiling is evolving in the forensics community towards introducing massively parallel sequencing (MPS) as a complement to capillary electrophoresis (CE). Obstacles remain however before this technology can become routine in forensic casework, such as the development of more efficient bioinformatics solutions and recommendations concerning data analyses. LÄS MER