Sökning: "stroma"

Visar resultat 1 - 5 av 21 uppsatser innehållade ordet stroma.

  1. 1. Assessment and evaluation of heterogeneity in data from immune infiltration spatial niches in lung cancer

    Kandidat-uppsats, Lunds universitet/Matematisk statistik

    Författare :Mahta Keivani Najafabadi; [2023]
    Nyckelord :Mathematics and Statistics;

    Sammanfattning : The protein biomarker expressions in three types of sampled immune INFILTration spatial niches in lung cancer tissue were measured using the new technology Digital Spatial Profiler (DSP). The three types of immune INFILTration that were observed in lung tumors were STROMA identified as immune cells separate from tumor cells, Tertiary lymphoid structures (TLS) identified as dense structures of organized immune cells and finally Infiltraterate where immune cells dispersed among and in direct contact with tumor cells (INFILT). LÄS MER

  3. 2. Studie av celltillväxt hos kondrocyter och mesenkymala stromaceller från benmärg- en utvärdering av optimala odlingsförhållanden

    Kandidat-uppsats, Örebro universitet/Institutionen för hälsovetenskaper

    Författare :Sara Emilsson; [2023]
    Nyckelord :Articular cartilage; chondrocytes; mesenchymal stromal cells; viability; cell growth; Hyalint brosk; kondrocyter; mesenkymala stromaceller; viabilitet; celltillväxt;

    Sammanfattning : Introduktion: Hyalint brosk består av kondrocyter inbäddade i ett extracellulärt matrix som täcker alla kroppens synoviala leder. I dag är skador på hyalint brosk ett folkhälsoproblem med begränsade behandlingsmöjligheter. LÄS MER

  4. 3. Potency Analysis of Mesenchymal Stromal Cells Towards Innate and Adaptive Immune Cells

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Linn Garbers; [2023]
    Nyckelord :Mesenchymal stroma cells; T cells; interferon gamma; cytokines; tumor necrosis factor alpha; mesenkymala stromaceller; T-celler; interferon gamma; cytokiner; tumörnekrosfaktor alpha;

    Sammanfattning : Studien utvärderar egenskaper hos mesenkymala stromaceller (MSC) i passage 2 och 3. I ett samarbete mellan Cellcolabs och Karolinska Institutet (KI) genomfördes projektet med Katarina Le Blancs forskargrupp. LÄS MER

  5. 4. The Effect of Angiogenesis Inhibition on Tumor-Associated Granulocytes in an Orthotopic Model of High-Risk Neuroblastoma

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Maja Hammarström; [2022]
    Nyckelord :neuroblastoma; tumor angiogenesis; sunitinib; SU11248; tumor-associated neutrophils; immunohistochemistry;

    Sammanfattning : Background: Neuroblastoma is the most common extracranial solid tumor in children. The survival rate in high-risk neuroblastoma is less than 50 % despite intensive multimodal therapy, and there is thus an immense need for new treatment options. LÄS MER

  7. 5. Knockout studies of Panc1 cells

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Martin Sundin; [2021]
    Nyckelord :PDAC; crosstalk; stroma; spheroid; western blot; viability; gemcitabine.; PDAC;  verh rning; stroma; sf roid; western blot; viabilitet; gemcitabine.;

    Sammanfattning : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancerwith very few available treatment options of which none has great effect.Cancer cells and stromal cells such as stellate cells which exist in abundancein PDAC interact by crosstalk, resulting in a tumorigenic collective response. LÄS MER