Sökning: "SU11248"

Hittade 2 uppsatser innehållade ordet SU11248.

1. 1. The Effect of Angiogenesis Inhibition on Tumor-Associated Granulocytes in an Orthotopic Model of High-Risk Neuroblastoma

   Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Maja Hammarström; [2022]
   Nyckelord :neuroblastoma; tumor angiogenesis; sunitinib; SU11248; tumor-associated neutrophils; immunohistochemistry;

   Sammanfattning : Background: Neuroblastoma is the most common extracranial solid tumor in children. The survival rate in high-risk neuroblastoma is less than 50 % despite intensive multimodal therapy, and there is thus an immense need for new treatment options. LÄS MER

3. 2. The effect of deactivation or silencing of tumor stroma with angiogenesis inhibitor on malignancy of tumor metastases

   Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Nataly Tachijian; [2021]
   Nyckelord :neuroblastoma; SU11248; angiogenesis; tumor-associated macrophages; immunohistochemistry;

   Sammanfattning : Background: Neuroblastoma (NB) is a pediatric tumor in infants and young children. The survival rate is only around 50 percent for high-risk NB despite advanced and intense multi-modal therapy. Current research aims to find new effective treatment additional to modern therapy to improve prognosis of high-risk NB in children. LÄS MER