Sökning: "targetted protein degradation"
Hittade 1 uppsats innehållade orden targetted protein degradation.
1. Chemical design, synthesis and biological evaluation of novel proteolysis targeting chimeras (PROTACs) for the degradation of NUDT5
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Preparativ läkemedelskemiSammanfattning : Proteolysis targeting chimeras (PROTACs) represent a new modality in drug design. They are bifunctional molecules; with one end, they bind to a protein of interest, and with the other end, they bind to endogenous E3 ligases. LÄS MER
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