Sökning: "DCE-MRI"

Visar resultat 1 - 5 av 7 uppsatser innehållade ordet DCE-MRI.

  1. 1. Implementation and Evaluation of Uncertainty Estimation for Advanced Pharmacokinetic Models in DCE-MRI

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Jonas Höglund; [2022]
    Nyckelord :;

    Sammanfattning : The goal of this report is to develop code in Python that implements and evaluates a multivariate linear error propagation for commonly used DCE-MRI models. Two pharmoacokinetic models (PK-models) were tested; modified Kety model and two-compartment exchange model. LÄS MER

  3. 2. Non-Rigid Volume Registration For DCE-MRI Using Deep Learning

    Master-uppsats, Lunds universitet/Matematik LTH

    Författare :Jonatan Ferm; [2021]
    Nyckelord :Mathematics and Statistics;

    Sammanfattning : In dynamically contrast enhanced magnetic resonance imaging (DCE-MRI) mul-tiple images are generated for a single scan. Before further analysis can be done,the images needs to be registered. Traditional registration techniques can yieldimpressive results, but are often very computationally expensive. LÄS MER

  4. 3. Method for the classification of brain cancer treatment's responsiveness via physical parameters of DCE-MRI data

    Master-uppsats, Stockholms universitet/Fysikum

    Författare :Georgia Kanli; [2015]
    Nyckelord :DCE-MRI; pharmacokinetic modeling; perfusion imaging; brain tumor; patient classification;

    Sammanfattning : Tumors have several important hallmarks; anomalous and heterogeneous behaviors of their vascular structures, and high angiogenesis and neovascularization. Tumor tissue presents high blood flow (F) and extraction ratio (E) of contrast molecules. LÄS MER

  5. 4. Validation and Robustness Analysis of Dynamic Contrast Enhanced MRI

    Master-uppsats, Umeå universitet/Institutionen för fysik

    Författare :Samuel Fransson; [2015]
    Nyckelord :MRI; DCE-MRI; Dynamic Contrast Enhanced MRI; Validation; Simulation;

    Sammanfattning : In Dynamic Contrast Enhanced MRI there are several steps from the initial signal to obtaining the pharmacokinetic parameters for tumor characterization. The aim of this work was to validate the steps in the flow of data focusing on T1-mapping, Contrast Agent (CA)-quantification and the pharmacokinetical (PK) model, using a digital phantom of a head. LÄS MER

  7. 5. Improving the Modeling Framework for DCE-MRI Data in Hepatic Function Evaluation

    Master-uppsats, Institutionen för medicin och hälsa; Hälsouniversitetet

    Författare :Anneli Mossberg; [2013]
    Nyckelord :DCE-MRI; modeling; irregular sampling; spatio-temporal standard deviation estimation; sampling time optimization; regional optimization; liver function evaluation; systems biology;

    Sammanfattning : Background Mathematical modeling combined with prior knowledge of the pharmacokinetics of the liver specific contrast agent Gd-EOB-DTPA has the potential to extract more information from Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) data than previously possible. The ultimate goal of that work is to create a liver model that can describe DCE-MRI data well enough to be used as a diagnostic tool in liver function evaluation. LÄS MER