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Hittade 5 uppsatser som matchar ovanstående sökkriterier.

  1. 1. Effects of pharmaceutical excipients on the chemical stability of therapeutic proteins in a parenteral formulation

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Emmanuel Gulangayan Deniola; [2022]
    Nyckelord :Chemical stability; protein degradation; GA-Z; somatropin; pharmaceutical excipients; liquid chromatography; pharmaceutical technology; Chemistry;

    Sammanfattning : Proteins and peptides are widely used for the prevention, management, and cure of various illnesses. This vast therapeutic potential represents a significant portion of the pharmaceutical industry in the form of vaccines, antibodies, enzymes, and other protein-based therapeutics. LÄS MER

  3. 2. Spårmängdsanalys av explosivämnen

    Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Cheryl Loorents; [2020]
    Nyckelord :Spårmängdsanalys; explosivämnen; R-salt; TNT; PETN; LC-UV; SPE; LC-MS;

    Sammanfattning : There is an alarming increase of explosions with devastating consequences, the ultimate being loss of life. Furthermore, these kinds of substances have a toxic effect on animals, nature and humans if they are incorrectly disposed. LÄS MER

  4. 3. Development of separation method for analysis of oligonucleotides using LC-UV/MS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk farmaceutisk kemi

    Författare :Björs Ida; [2018]
    Nyckelord :Oligonucleotides; UPLC; liquid chromatography; time of flight; mass spectrometry; reversed-phase weak anion exchange; AcclaimTM Mixed Mode WAX-1; DNAPacTM RP; ACQUITY UPLC BEH C18;

    Sammanfattning : Introduction Oligonucleotides are short nucleic acid chains, usually 19-27mer long. They bind to their corresponding chain, making a specific inhibition possible. In pharmaceuticals, this can be used to inhibit the expression of a gene or protein of interest. LÄS MER

  5. 4. Chemical Modifications of Hyaluronan using DMTMM-Activated Amidation

    Uppsats för yrkesexamina på avancerad nivå, Syntetisk organisk kemi

    Författare :Sara Rydergren; [2013]
    Nyckelord :;

    Sammanfattning : An alternative approach to chemically modifying hyaluronan (HA) has been investigated. The triazine derivative 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium (DMTMM) has been used to activate carboxylic groups on HA, which react further to form stable amide bonds with primary and secondary amines. LÄS MER

  7. 5. Development of LC-QTOF method for analysis of extracts from urinary catheters

    Uppsats för yrkesexamina på avancerad nivå,

    Författare :Kajsa Ekvall; [2012]
    Nyckelord :;

    Sammanfattning : Urinary catheters are made of polymers which in some cases contain a number of additives in order to get certain properties such as mechanical flexibility and prolonged shelf-life. To prove costumer safety, a manufacturer need to extract and analyse  these additives by a number of different methods. LÄS MER