Sökning: "MTS assay"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden MTS assay.

  1. 1. Investigating the cause of reduction of lactate production in Panc-1 cell lines when subjected to digitoxin

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Israel Tshibangu; [2021]
    Nyckelord :;

    Sammanfattning : Pancreatic ductal adenocarcinoma (PDAC) yet remains one of the top 10 most prevalent and top five most common cause of cancer-related deaths solely in the United States. Its metastatic deviation from most cancer types rends it one of the most subtle yet perturbating disease. LÄS MER

  3. 2. Studying the effects of Muscone on PANC-1 in vitro

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsovetenskaper

    Författare :Kyriaki Gerontaki; [2020]
    Nyckelord :;

    Sammanfattning : In this project cancer was viewed as a metabolic disorder. The study focused on the effect of synthetic muscone on PANC-1 cells. Synthetic muscone is a ketone. Some cancers lack the potential to metabolise ketone bodies, mainly due to mitochondrial dysfunction. LÄS MER

  4. 3. Nox inhibitors : A potential future medicine for ischemia stroke

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsa och lärande

    Författare :Charlotte Jackson; [2018]
    Nyckelord :NOX inhibitors; reactive oxygen species; ROS; ischemia stroke;

    Sammanfattning : This study investigated the neuroprotective effects of novel small molecule NOX inhibitors after induction of an ischemic stroke model on Neuroblastoma cells (NB69). Previous findings show that high levels of reactive oxygen species (ROS) have been identified for playing a role in causing inflammation, cellular damage and apoptosis in many cardiovascular diseases. LÄS MER

  5. 4. Nox2/4 inhibition in NB69 during ischemia/reperfusion : Inhibition of ROS-production using M4, M107, and M114

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsa och lärande

    Författare :Hampus Johansson; [2017]
    Nyckelord :;

    Sammanfattning : Cerebral stroke has become one of the leading causes of death and disability worldwide. During an ischemic stroke, oxygen and nutrient deprivation occurs, which combined lead to cell starvation, anoxia, and eventually cell death. LÄS MER

  7. 5. Gene expression of MAP2K1 and Cyclin D1 in BDII rat model of Endometrial cancer

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Almir Budnjo; [2016]
    Nyckelord :biomedicine; endometrial cancer; gene expression; qPCR; BDII rat model; MAP2K1; CCND1; MTS assay; cell culturing; Taqman; MAPK signaling pathway;

    Sammanfattning : Endometrial adenocarcinoma (EAC) is the most frequently diagnosed gynecological cancer of the female genital tract in the Western world. Research studies in EC is difficult to conduct on human tumor samples due to the complex nature of tumor arousal and genetic heterogeneousness in the human population. LÄS MER