Sökning: "NHEJ"

Hittade 2 uppsatser innehållade ordet NHEJ.

1. 1. Compounds screening for the identification of novel drug to improve the Knock in efficiency mediated by CRISPR-Cas9

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Evangelia Anagnostou; [2023]
   Nyckelord :Genome editing; Knock in; HDR; CRISPR-Cas9; screening; NHEJ;

   Sammanfattning : Genome editing is an exciting field that allows for the precise modification of an organism's DNA. One of the most advanced tools in this area is CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9), which creates a DSB (Double-strand break) at a specific location in the genome. LÄS MER

3. 2. The genes controlling NHEJ in neuroblastoma

   Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsovetenskaper

   Författare :Lola Riazantseva; [2021]
   Nyckelord :;

   Sammanfattning : This study has been made in order to investigate the non-homologous end joining (NHEJ) pathway and the genes involved in this system, particularly their roles in neuroblastoma. The study aims to identify the expression levels of genes included in the pathway in neuroblastoma samples of varying clinical characteristics, classifications and behaviors to see how these differs. LÄS MER