Sökning: "Pyrrolidines"

Hittade 1 uppsats innehållade ordet Pyrrolidines.

  1. 1. Synthesis of Substituted Pyrrolidines

    Master-uppsats, KTH/Skolan för kemivetenskap (CHE)

    Författare :Olof Sjölin; [2016]
    Nyckelord :Pyrrolidines; Multistep synthesis; Fragment-based drug design; Drug discovery; Organic chemistry;

    Sammanfattning : The task of medicinal chemists in a drug discoveryproject is to synthesize/design analogues to the screening hits, simultaneouslyincreasing target potency and optimizing the pharmacological properties.  This requires a wide selection of moleculesto be synthesized, where both synthetic feasibility and price of startingmaterials are of great importance. LÄS MER