Sökning: "Spatial Variation"

Visar resultat 1 - 5 av 255 uppsatser innehållade orden Spatial Variation.

  1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemi

    Författare :Maryam Dost; [2024]
    Nyckelord :Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Sammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER

  3. 2. FROM SPACE TO THE SUBSURFACE. Examining Relations Between Vegetation Indices and Local Groundwater Storage.

    Master-uppsats, Göteborgs universitet/Institutionen för geovetenskaper

    Författare :Gustav Antonsson; [2023-11-06]
    Nyckelord :;

    Sammanfattning : This study aimed to examine the relationship between vegetation indices, NDVI and NDWI, and groundwater levels in the county of Kalmar, utilizing correlation and regression analysis. Further, by examining related geospatial features the study aimed to interpret the statistical outcomes to identify significant temporal and spatial patterns. LÄS MER

  4. 3. Gun violence and school achievement: Evidence from Sweden

    Master-uppsats, Göteborgs universitet/Graduate School

    Författare :Ellinor Stensson; [2023-06-29]
    Nyckelord :Gun violence; Educational outcomes; Sweden;

    Sammanfattning : This paper examines how educational outcomes in grade six are affected by gun violence that occurs in proximity to primary schools in Sweden. With geo-referenced data on gun violence over the period between 2018 and 2022, the thesis geographically matches spatial data on 1,811 shootings with national test results in mathematics and background data on 2,304 Swedish primary schools. LÄS MER

  5. 4. Platsens betydelse för växtnäringsläckage från jordbruksmark i Sverige

    Kandidat-uppsats, SLU/Dept. of Soil and Environment

    Författare :Frida Lundell; [2023]
    Nyckelord :kväve- och fosforutlakning; rumslig variation; långtidsövervakning;

    Sammanfattning : Växtnäringsläckage av kväve (N) och fosfor (P) från jordbruksmark tillför näringsämnen till hav och vattendrag. Det är viktigt att minska transporten av N och P av flera anledningar, då det bland annat är en stor bidragande faktor till övergödning. LÄS MER

  7. 5. Assessment and evaluation of heterogeneity in data from immune infiltration spatial niches in lung cancer

    Kandidat-uppsats, Lunds universitet/Matematisk statistik

    Författare :Mahta Keivani Najafabadi; [2023]
    Nyckelord :Mathematics and Statistics;

    Sammanfattning : The protein biomarker expressions in three types of sampled immune INFILTration spatial niches in lung cancer tissue were measured using the new technology Digital Spatial Profiler (DSP). The three types of immune INFILTration that were observed in lung tumors were STROMA identified as immune cells separate from tumor cells, Tertiary lymphoid structures (TLS) identified as dense structures of organized immune cells and finally Infiltraterate where immune cells dispersed among and in direct contact with tumor cells (INFILT). LÄS MER