Sökning: "c-Myc"
Visar resultat 1 - 5 av 6 uppsatser innehållade ordet c-Myc.
1. Investigating Minor States of the Oncoprotein N-MYC, with Focus on Proline Cis/Trans Isomerisation using NMR Spectroscopy
Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologiSammanfattning : MYC is a family of three regulator genes that codes for transcription factors. Expression of Myc proteins from MYC genes is found to be deregulated in 70 % of all cancer forms. The three human homologs C-Myc, N-Myc and L-Myc are mainly associated with cancer in the lymphatic system, nerve tissues and lung cancer, respectively. LÄS MER
2. Investigating the cause of reduction of lactate production in Panc-1 cell lines when subjected to digitoxin
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Pancreatic ductal adenocarcinoma (PDAC) yet remains one of the top 10 most prevalent and top five most common cause of cancer-related deaths solely in the United States. Its metastatic deviation from most cancer types rends it one of the most subtle yet perturbating disease. LÄS MER
3. Canine transmissible venereal tumour
Kandidat-uppsats, SLU/Dept. of Anatomy, Physiology and BiochemistrySammanfattning : Canine Transmissible Venereal Tumour (CTVT) är en unik smittsam tumörsjukdom. Likt en parasit är den naturligt överförbar mellan individer inom familjen Canidae via transplantation av levande tumörceller, framför allt genom parning. LÄS MER
4. Metoder som minskar bildning av teratom vid in vivo transplantation av inducerade pluripotenta celler
Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public HealthSammanfattning : Inducerad pluripotens innebär att man inducerar mogna celler till att övergå i ett pluripotent stadium och bilda så kallade inducerade pluripotenta celler (iPS-celler). Detta görs till exempel genom viral integration av transkriptionsfaktorerna octamer-binding transcription factor 3 och 4 (Oct3/4), sex determining region Y-box 2 (Sox2), Krüppel-like factor 4 (Klf4) och c-Myc. LÄS MER
5. Luciferase Expression Vectors For Analyzing RNA Interference within the MYCN 3'UTR
Kandidat-uppsats, Lunds universitet/Kemiska institutionenSammanfattning : The gene MYCN encodes a transcription factor with a fundamental role in many neuroendocrine tumors, especially neuroblastoma. The gene and protein are very similar to the closely related c-Myc protein, except for the 3´untranslated region (3´UTR), suggesting that it may be an important factor in determining their very different expression pattern at the post-transcriptional level. LÄS MER