Sökning: "cellular reprogramming"

Hittade 3 uppsatser innehållade orden cellular reprogramming.

1. 1. Panacea: Predicting anti-aging combinations from expression analysis

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Ashwini Jatti; [2023]
   Nyckelord :aging; machine learning; drug combinations; rejuvenation; cellular reprogramming;

   Sammanfattning : Identifying interventions, such as drugs, that can counteract the effects of aging is crucial due to the complex nature of the aging process, which involves multiple biological processes. By targeting these processes, interventions have the potential to promote healthy aging. LÄS MER

3. 2. Phenotypic profiling and drug screening in Rhabdomyosarcoma cell lines

   Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Laura Martina Lang; [2022]
   Nyckelord :Rhabdomyosarcoma; Phenotypic profiling; Phenotypic drug screening;

   Sammanfattning : Rhabdomyosarcoma (RMS) is a type of soft tissue sarcoma that mainly occurs in children. RMS can be divided into two subtypes embryonal (ERMS) and alveolar (ARMS). The ARMS subtype can be especially aggressive when a balanced chromosomal translocation is present. LÄS MER

4. 3. Establishing iPSCs as a method to model neurodevelopment in Down’s syndrome

   Master-uppsats, Institutionen för biologisk grundutbildning

   Författare :Margarita Bartish; [2012]
   Nyckelord :induced pluripotent stem cells; stem cells; disease modeling; cellular reprogramming;

   Sammanfattning : The derivation of pluripotent stem cells (now termed induced pluripotent stem cells, iPSC) from mature somatic cells was a finding of seminal importance to fundamental cell biology. Thus established iPSC technology has been predicted to advance fields that previously relied on the ethically disputed use of embryonic stem cells. LÄS MER