Sökning: "galektin"

Hittade 3 uppsatser innehållade ordet galektin.

1. 1. Design, synthesis, and evaluation of 1-phenylethanol and C2 threitol derivatives as non-pyranose galactose-mimicking inhibitors of Galectin-3

   Master-uppsats, Lunds universitet/Centrum för analys och syntes

   Författare :Qrystal Cruz Giron; [2023]
   Nyckelord :Galectin-3; Galectin-3 inhibitor; 1-phenylethanol; C2 threitol derivative; galactose-mimicking inhibitor; organic chemistry; Chemistry;

   Sammanfattning : Galectins are cytosolic protein family involved in several biological functions such as cell differentiation, cell migration and apoptosis amongst many others. Their presence is also substantial in diseases including acute inflammation, fibrosis, allergies, and cancer. LÄS MER

3. 2. Design och syntes av potentiella inhibitorer för galektin-1

   Kandidat-uppsats, Lunds universitet/Kemiska institutionen

   Författare :Victoria Ullbin; [2022]
   Nyckelord :galektin-1; inhibitor; galektin; cancer; organic chemistry; Chemistry;

   Sammanfattning : Galectin-1 is a member of the carbohydrate-binding protein family galectins. Galectins are involved in the immune system. However, in cancer growth, galectin-1 is overproduced to not make the immune system respond. Therefore, inhibitors of the protein were synthesized to make the immune system approach the cancer and respond. LÄS MER

4. 3. Investigation of α-thioaryl galactopyranosides to improve affinity towards Galectin-9N

   Kandidat-uppsats, Lunds universitet/Kemiska institutionen

   Författare :Sofi Gummesson; [2018]
   Nyckelord :organic chemistry; organisk kemi; Chemistry;

   Sammanfattning : Galectins are a family of carbohydrate recognition proteins involved in modulation of cell signaling and cell adhesion. galectin-9 especially is involved in regulation of the immune response. In this work, galectin-9N inhibitors have been designed, synthesized and evaluated. LÄS MER