Sökning: "Galectin-3 inhibitor"
Hittade 4 uppsatser innehållade orden Galectin-3 inhibitor.
1. Design, synthesis, and evaluation of 1-phenylethanol and C2 threitol derivatives as non-pyranose galactose-mimicking inhibitors of Galectin-3
Master-uppsats, Lunds universitet/Centrum för analys och syntesSammanfattning : Galectins are cytosolic protein family involved in several biological functions such as cell differentiation, cell migration and apoptosis amongst many others. Their presence is also substantial in diseases including acute inflammation, fibrosis, allergies, and cancer. LÄS MER
2. Design och syntes av potentiella inhibitorer för galektin-1
Kandidat-uppsats, Lunds universitet/Kemiska institutionenSammanfattning : Galectin-1 is a member of the carbohydrate-binding protein family galectins. Galectins are involved in the immune system. However, in cancer growth, galectin-1 is overproduced to not make the immune system respond. Therefore, inhibitors of the protein were synthesized to make the immune system approach the cancer and respond. LÄS MER
3. Synthesis of fluorescent carbohydrate coumarin hybrids via a three-component reaction : nanomolar galectin-3 inhibitor
Master-uppsats, Lunds universitet/Kemiska institutionenSammanfattning : Galectins play an important role in inflammation, immunity, cancer progression and are potential targets for novel anti-cancer and anti-inflammatory compounds. Coumarin thiodigalacoside hydrid had proved to be potent, nanomolar, and selective inhibitor of galectin-3. LÄS MER
4. An approach to diketone-galectin-3 inhibitor
Kandidat-uppsats, Lunds universitet/Kemiska institutionenSammanfattning : In many biological mechanisms galectins play important roles. The galectins are important in inflammation, immunologic response and cancer. A key function of galectins is cross-linking of their glycoprotein ligands which are connected with the biological activities. Carbohydrate recognition domains (CRD) are responsible for the cross-linking. LÄS MER
