Sökning: "oxygen-15-labelled water"

Hittade 2 uppsatser innehållade orden oxygen-15-labelled water.

1. 1. Quantification of cerebral blood flow with 15O-water PET : A comparison study between PET/CT and PET/MR and two different blood sampling instruments

   Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik; Umeå universitet/Diagnostisk radiologi

   Författare :Amanda Eriksson; [2021]
   Nyckelord :Cerebral Blood Flow; CBF; oxygen-15-labelled water; PET CT; PET MR; Quantification of CBF; Image Derived Input Function; IDIF; Blood Sampled Input Function; BSIF; Arterial Input Function; AIF; Tracer Kinetic Modelling; Single Tissue Compartmental Model; 1TCM;

   Sammanfattning : Cerebral blood flow quantification is a vital diagnostic tool for disease monitoring and used for diagnosing a variation of pathological conditions. The human brain requires roughly about 20 % of the total cardiac output to sustain normal functioning, hence the perfusion of blood is an important factor to deliver oxygenated blood. LÄS MER

3. 2. A porcine type 1 Diabetes Mellitus model, for non-invasive in vivo imaging of the glucagon-like peptide-1 receptor in the pancreas, using [68Ga]Ga-DO3A-VS-Cys40-conjugated synthetic exendin-4 in PET-CT

   Master-uppsats, SLU/Dept. of Clinical Sciences

   Författare :Susanne Andréasson; [2014]
   Nyckelord :Exendin-4; GLP-1R; pig; beta cell imaging; beta cell mass; Exendin-4; gris; betacellsmassan; PET-CT;

   Sammanfattning : Diabetes mellitus is a rising epidemic throughout the world and there is currently great interest in quantifying the beta-cell mass (BCM) in vivo non-invasively. In the present experiment, the feasibility of in vivo imaging of the glucagon-like peptide-1 receptor (GLP-1R) in beta-cells was examined, using the positron emission tomography (PET) tracer [68Ga]Ga-DO3A-VS-Cys40-exendin-4 as a marker, in native pancreatic beta-cells of a porcine diabetic animal model and healthy controls. LÄS MER