Sökning: "Chronic lymphocytic leukemia"

Hittade 5 uppsatser innehållade orden Chronic lymphocytic leukemia.

  1. 1. Explanation Methods for a Medical Image Classifier by Analysis of its Uncertainty

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Sanskar Gupta; [2022]
    Nyckelord :Uncertainty; Confidences; Calibration; Clustering; Multiclass classification;

    Sammanfattning : Over the last decade, neural networks have reached almost every field of science and technology. They have become a crucial part of various real-world applications, such as medical imaging. LÄS MER

  3. 2. Deciphering the ontogeny of unmutated and mutated subsets of Chronic Lymphocytic Leukemia

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Ahmed Mohamed; [2019]
    Nyckelord :CLL; NGS; mutated CLL; unmutated CLL; CD27 bright; CD27 dull; memory B cell; RNA-sequencing;

    Sammanfattning : Chronic Lymphocytic Leukemia (CLL) is a type of cancer that affects the B cells of the immune system causing problems in the process of producing antibodies. It can be sorted into mutated and unmutated CLL based on the percentage of somatic mutations in the Immunoglobulin Heavy chain Variable region (IgHV). LÄS MER

  4. 3. Role of Selective Estrogen Receptors B Agonist on Chronic Lymphocytic Leukemia Growth in Vitro

    Master-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknik

    Författare :Noor Salam; [2014]
    Nyckelord :Chronic lymphocytic leukemia; diarypropionitrile; estrogen receptor B;

    Sammanfattning : The estrogen receptor alpha (ERa) and estrogen receptor beta (ER~) have been demonstrated to be important for immune system regulation and studies have suggested an antiproliferative effect of ER~ in lymphoid malignancies. We have studied the expression of ERa and ER~ in peripheral blood mononuclear cells from patients with chronic lymphocytic leukemia (CLL). LÄS MER

  5. 4. Effects of protein kinase inhibitors on chronic lymphocytic leukemia (CLL) cells

    Master-uppsats, Institutionen för klinisk och experimentell medicin; Hälsouniversitetet

    Författare :Hasan Imam; [2009]
    Nyckelord :;

    Sammanfattning : B cell Chronic lymphocytic leukemia (B-CLL) is a neoplastic disorder characterized by accumulation of B lymphocytes due to uncontrolled growth and resistance to apoptosis. Src family kinases (SFKs) are non receptor tyrosine kinases present in the cytosol, which couple with downstream B cell receptor signaling and thus mediate growth, survival, proliferation and antiapoptosis. LÄS MER

  7. 5. Effect of combined treatment with R-(+)-methanandamide and chemotherapeutic drugs in mantle cell lymphoma and chronic lymphocytic leukemia : MCL

    Magister-uppsats, Mälardalens högskola; Akademin för hälsa, vård och välfärd; Akademin för hållbar samhälls- och teknikutveckling

    Författare :Vasanthakumar Thirugnanam; []
    Nyckelord :;

    Sammanfattning : Mantle cell lymphoma (MCL) is a non-Hodgkin B-cell lymphoma with very bad prognosis. The genetic hallmark of MCL, is the translocation t(11;14)(q13;q32) which leads to overexpression of cyclin D1, a D-type cyclin that is not usually expressed at high levels in normal B lymphocytes. LÄS MER