Sökning: "DNA gyrase"

Hittade 2 uppsatser innehållade orden DNA gyrase.

1. 1. Towards time-resolved cryo-EM of SARS-CoV-2 replication-transcription complex and Staphylococcus aureus DNA gyrase

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Anna Králová; [2023]
   Nyckelord :time-resolved cryo-EM; DNA gyrase; SARS-CoV-2; replication-transcription complex; protein purification;

   Sammanfattning : Time-resolved cryo-EM has already provided ground-breaking discoveries in various fields, including structural biology, biochemistry, and drug development. Compared to traditional structural biology methods where mostly stabilized conformations are reconstructed, the main advantage of time-resolved cryo-EM is its ability to capture dynamic processes in biological samples at near-atomic resolution, which allows for studying biological structures as they change and interact in real-time. LÄS MER

3. 2. Vilka potentiella behandlingsalternativ finns det mot bakteriella infektionssjukdomar som ligger i fas 2-3 studier eller som man bedriver forskning på?

   Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

   Författare :Linnea Johansson; [2018]
   Nyckelord :antibiotika; nanopartiklar; nanopartikel; resistens; antibiotikaresistens; ENABLE; ENABLE-projektet;

   Sammanfattning : Resistance against antibiotics has become a global world problem. The effect of antibiotics is affected by the resistant bacteria and they cause infections that are difficult to treat. This is a major burden on the healthcare and leads to increased mortality. Globally, about 700,000 people die each year because of antibiotic resistance. LÄS MER