Sökning: "DNA-damage"
Visar resultat 1 - 5 av 26 uppsatser innehållade ordet DNA-damage.
1. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma
Master-uppsats, KTH/ProteinvetenskapSammanfattning : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. LÄS MER
2. Toxicological analysis of Pyraclostrobin and Cyprodinilon Zebrafish larvae
Kandidat-uppsats, Örebro universitet/Institutionen för naturvetenskap och teknikSammanfattning : Cyprodinil and pyraclostrobin are widely used pesticides to protect many plants from attack of microorganisms and fungal diseases. Although cyprodinil and pyraclostrobin exist in the aquatic environment at low concentration, their leftovers in the ecosystems lead to oxidative damage and interfere development in aquatic animals at environmental-relevant concentration. LÄS MER
3. The circadian rhythm of the cells is dependent of the pH of the cell
Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsovetenskaperSammanfattning : Circadian rhythms are endogenic autonomous oscillators of physiological activities resulting from 24-hour day/night cycles. Circadian rhythms regulate a wide variety of metabolic and physiological functions. This allows the organism to control its molecular, biochemical, physiological, and behavioural processes. LÄS MER
4. Comet assay: Monitoring time-dependent DNA-fragmentation in two different types of cells, optimizing Flash-comet method for pig sperm analysis
Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskapSammanfattning : DNA-damage, caused by different factors such as oxidative stress in cells, is common in living organisms. The damage includes DNA-fragmentation, such as single- and double strands breaks. LÄS MER
5. Deciphering regulatory mechanism influencing qepA efflux pump expression in Escherichia coli
Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiSammanfattning : QepA is a plasmid-mediated efflux pump found in some strains of Escherichia coli, in which it significantly elevates the resistance against quinolones. The protein has similarities with 14-TMS major facilitator superfamily transporters and is situated in the inner membrane of the bacteria. LÄS MER