Sökning: "Drug release"

Visar resultat 1 - 5 av 59 uppsatser innehållade orden Drug release.

  1. 1. Evaluation of different block-copolymer coatings of iron oxide nanoparticles by flash nanoprecipitation

    Master-uppsats, KTH/Fiber- och polymerteknologi

    Författare :Felix Bogdan; [2023]
    Nyckelord :Nanopartiklar; organisk katalysator; ROP; block-sampolymerer PL G A; oljesyra IONPs; Nanoparticles; organic catalyst; ROP; block-copolymers PL G A; oleic acid IONPs;

    Sammanfattning : Nanopartiklar (NP) erbjuder unika möjligheter för medicinska tillämpningar, inklusive kontrollerad frisättning av cancerläkemedel, användning som bildkontrast vid avbildningsprocedurer eller hypertermisk behandling av cancerceller. Flash nanoprecipitation (FNP) producerar NPs för att kombinera dessa tillämpningar i en snabb, billig och skalbar beläggningsprocess. LÄS MER

  3. 2. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Beräkningsbiologi och bioinformatik

    Författare :Linde Brokmar; [2023]
    Nyckelord :Protein design; de novo design; protein engineering; generative ai; machine learning; peptide binders; AF2; EvoBind; RFdiffusion; ProteinMPNN;

    Sammanfattning : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. LÄS MER

  4. 3. MD simulation study on drug release from HPMCAS-based amorphous solid dispersions upon reaching cell membrane

    Master-uppsats, Uppsala universitet/Institutionen för farmaci

    Författare :Razan Hasani; [2022]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Lipodisks for Dual Delivery of SN-38 and Melittin

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för kemi - Ångström

    Författare :Nathalie Alanko; [2022]
    Nyckelord :;

    Sammanfattning : The use of drug delivery systems based on liposomes or lipodisks as nanocarriers have been proven to have several advantages compared to conventional chemotherapy when drug is administered in free form. Lipodisks are not as well studied as liposomes, but can be reliably produced with a smaller size which is an important factor for efficient accumulation at the target site and penetration of tumor tissue. LÄS MER

  7. 5. On-chip characterization of hydroxyapatite with different topography

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för materialvetenskap

    Författare :Maja Grape; [2022]
    Nyckelord :biomaterials; calcium-deficient hydroxyapatite; microfluidic systems;

    Sammanfattning : Biomaterials are defined as non-viable materials whose functions strives to interact with biological systems, this makes biomaterials suitable for medical devices and applications. Biomaterials biological properties must be thoroughly investigated and evaluated in order to be approved for clinical usage. LÄS MER