Sökning: "gene silencing"

Visar resultat 1 - 5 av 18 uppsatser innehållade orden gene silencing.

  1. 1. Spray Induced Gene Silencing in Phytophthora infestans : investigating exogenous dsRNA application for the control of potato late blight

    Master-uppsats, SLU/Dept. of Plant Breeding (from 130101)

    Författare :Poorva Sundararajan; [2024]
    Nyckelord :Phytophthora infestans; RNAi; potato late blight; gene silencing; SIGS;

    Sammanfattning : Phytophthora infestans is an oomycete pathogen and the causal agent of late blight disease in potato and tomato. Even today, it causes massive loss to crop and economy worldwide. Current disease control strategies include breeding for resistance and extensive fungicide spray. LÄS MER

  3. 2. Investigating the expression and function of RNA-binding protein FUBL-1 in C. elegans

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Védís Mist Eyju Agnadóttir; [2023]
    Nyckelord :;

    Sammanfattning : RNA interference (RNAi) is an important mechanism of gene silencing in Caenorhabditis elegans, in which short RNAs direct sequence-specific silencing of gene expression mediated by Argonaute proteins. RNAi in C. LÄS MER

  4. 3. Finding the physiological function of the enzyme GPCAT. : a gene expression study using Arabidopsis plants with silenced GPCAT gene

    Kandidat-uppsats, SLU/Dept. of Plant Breeding (from 130101)

    Författare :Ida Hallström; [2022]
    Nyckelord :enzyme GPCAT; gene expression; glycerophosphocholine acyltransferase; GPCAT; PC recycling pathway; physiological function; sphingolipids;

    Sammanfattning : The aim of this project was to study the enzyme Glycerophosphocholine Acyltransferase (GPCAT) and try to find its physiological function. The biochemical reaction that the enzyme GPCAT catalyses is known, but its physiological function, e.g. why and when plants need the enzyme GPCAT, is unknown. LÄS MER

  5. 4. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles

    Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Författare :Marc Pielies Avellí; [2022]
    Nyckelord :Cancer Driver CD Gene; Histone Post-Translational Modifications PTMs ; Convolutional Neural Networks CNNs .; Physics and Astronomy;

    Sammanfattning : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. LÄS MER

  7. 5. Search for the Argonaute protein that governs miRNA regulation in Dictyostelium discoideum

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Miranda Åström; [2021]
    Nyckelord :Argonaute proteins; RNA interference; miRNA; 3xFLAG-tag;

    Sammanfattning : MicroRNAs are small non-coding RNAs that regulate gene expression through RNA interference. These small RNAs enact gene silencing by forming a RNA-inducing silencing complex together with the effector protein Argonaute. The function of the Argonautes in the social amoeba Dictyostelium discoideum is not yet fully understood. LÄS MER