Sökning: "insulinoma"

Visar resultat 1 - 5 av 6 uppsatser innehållade ordet insulinoma.

  1. 1. Evaluation of an equine-optimized enzyme-linked immunosorbent assay for the determination of serum insulin in canine and feline samples

    Kandidat-uppsats, Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Författare :Ylva Moberg; [2018]
    Nyckelord :Cross-reactivity; hypoglycaemia; immunoassay; insulinoma; validation;

    Sammanfattning : Background: Insulin is an important hormone for glucose homeostasis. It is released from β-cells in the endocrine pancreas as a response to increased concentrations of plasma glucose. The major effect of insulin is the facilitation of cellular uptake and storage of glucose as glycogen. LÄS MER

  3. 2. Metodjämförelse mellan två olika enzyme-linked immunosorbent assays (Medizym ICA screen och 2Screen islet cell autoantibody ELISA-kit) för mätning av islet cell antibodies, ICA

    Kandidat-uppsats, Högskolan Kristianstad/Sektionen för lärande och miljö

    Författare :Rana Elji; [2016]
    Nyckelord :ELISA; ICA; Sensitivity; Specificity; Type 1-diabetes; GADA; IAA; IA-2A; ZnT8A; ELISA; ICA; Sensitivitet; Specificitet; Typ 1-diabetes; GADA; IAA; IA-2A; ZnT8A;

    Sammanfattning : Type 1 diabetes (T1D) is regarded as an autoimmune disease. Beta cells, which produces insulin in pancreas are attacked by islet cell antibodies (ICA). This leads to gradual destruction of the beta cell, which in turn cause high level of glucose in the blood because the regulator "insulin" has disappeared. LÄS MER

  4. 3. Do Serglycin Related Alterations of Thrombocytes and Myeloid Cells Affect Tumor Progression and Behavior

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Kjersti Marie Hjelle; [2015]
    Nyckelord :Serglycin; Thrombocytes; Cancer; Spontaneous Insulinoma; RIP1-Tag2; Myeloid cells; Macrophages; Flowcytometri; FACS; CD115; CD31; CD11b; Gr-1; Ly-6G;

    Sammanfattning : Investigation of tumor growth has traditionally been studied focusing only on the cancer cells. However, tumors consist of a complex tissue organization where heterotypic signaling occurs between different cell types. LÄS MER

  5. 4. Role of TRPV1 channel and P2Y1 receptor in Ca2+ signalling in β-cells : A study by single cell microfluorometry

    Master-uppsats, Institutionen för fysik, kemi och biologi

    Författare :Kalaiselvan Krishnan; [2011]
    Nyckelord :Insulin exocytosis; P2Y1; tolbutamide; ADPr; microfluorometry; Islets of langerhans; β-cells; calcium signaling; signal transduction.;

    Sammanfattning : Increase in the cytoplasmic Ca2+ concentration ([Ca2+]i) in the β-cells triggers insulin exocytosis. Among the Ca2+ channels present in the plasma membrane, the transient receptor potential (TRP) channels receptors are currently of great interest. LÄS MER

  7. 5. A study of TRPV1 and TRPV4 ion channels in the beta cells by using fura-2 based microfluorometry.

    Master-uppsats, Akademin för hållbar samhälls- och teknikutveckling

    Författare :Banina Hadrovic; [2009]
    Nyckelord :;

    Sammanfattning : The calcium ion (Ca2+) is an important ion that regulates many cellular functions including exocytosis, contraction of muscles, neural functions, fertilization and cell division. In the plasma membrane of cells there are different Ca2+ channels, including the transient receptor potential (TRP) family of cation channels. LÄS MER