Sökning: "microfluidic chip"

Visar resultat 1 - 5 av 41 uppsatser innehållade orden microfluidic chip.

1. 1. Microfluidic flow splitter shape optimization for high throughput

   Kandidat-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

   Författare :Christoffer Papamoustos Palmér; Joel Linder; [2023]
   Nyckelord :Genetic algorithms; Lab-on-a-chip; Optimization; Acoustofluidics; Microfluidics; Technology and Engineering;

   Sammanfattning : Due to an increasing incidence rate, the need for new effective methods for diagnosing cancer are of high importance. Studies have shown that circulating tumor cells, CTCs, have great potential as a diagnostic biomarker. Acoustophoresis is a label free method, capable of separating CTCs from red blood cells in a blood sample. LÄS MER

3. 2. Buffer modification: A case study with polystyrene beads, DU145-, and MCF7 cell lines

   Master-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

   Författare :Olivia Hansson Rengbrandt; [2023]
   Nyckelord :Technology and Engineering;

   Sammanfattning : Separation of cancer cells gives advantages in understanding the disease, guiding treatment decisions, and facilitating drug development. Overall, separation plays an important role in biological research. Acoustophoresis is a technique that utilizes acoustic waves to separate particles and cells suspended in a buffer medium. LÄS MER

4. 3. Robust and Biocompatible Bonding of Hybrid Microfluidic Devices Using Off-Stoichiometric Thiol-ene Thermosets

   Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

   Författare :Peter Harris; [2023]
   Nyckelord :OSTE; OSTE ; Microfluidics; Thermoset; Bonding; Thermoplastics; Biocompatibility; OSTE; OSTE ; Mikrofluidik; Härdplast; Binding; Termoplaster; Biokompatibilitet;

   Sammanfattning : Some of the major obstacles the microfluidics industry has yet to overcome in order to facilitate large scale manufacturing of devices are costly back-end processes. Among these, bonding presents some of the most obvious difficulties and is often associated with structural deformation and surface modification. LÄS MER

5. 4. Active dielectrophoretic trapping for deterministic single-cell encapsulation in droplet microfluidics

   Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

   Författare :Prasanna Surana; [2023]
   Nyckelord :negative dielectrophoresis; droplet microfluidics; low conductivity medium; cell viability; COMSOL electric field simulation; joule heating; Rhodamine B temperature measurement; microfluidic chip cleaning; negativ dielektrofores; droppmikrofluidik; medium med låg konduktivitet; cellviabilitet; COMSOL elektrisk fältsimulering; jouleuppvärmning; Rhodamine B temperaturmätning; mikrofluidisk chiprengöring;

   Sammanfattning : The research work focuses on optimizing various parameters for controlling cells using negative dielectrophoresis and entrapping them in droplet microfluidics. This is achieved by developing a conductivity medium, combining CytoRecovery, BSA, and EDTA, to maintain a steady count of single cells with good viability over an extended period. LÄS MER

7. 5. Optimising microfluidic preparation of lipid sponge phase nanoparticles for biomolecule encapsulation

   Master-uppsats, Lunds universitet/Kemiteknik (CI)

   Författare :Owais Khalil; [2023]
   Nyckelord :Sponge phase; lipid nanoparticles; microfluidics; SAXS; cryo-TEM; DLS; chemical engineering; Chemistry;

   Sammanfattning : Drug delivery with lipid nanoparticles, especially sponge phase lipid nanoparticles (LNP), has been well studied because of its ability for drug encapsulation and transferring the drug through the cell membrane. The sponge phase LNP formulation could be affected by the molecular structure of the lipid, the temperature, pH, dilution, the buffer, and the addition of a stabiliser. LÄS MER