Evaluation of Robust Model Building Tools to Improve the Efficiency of Non-linear Mixed Effect Model Building Workflows

Detta är en Uppsats för yrkesexamina på avancerad nivå från Uppsala universitet/Institutionen för farmaci

Sammanfattning: Population PK models aim to describe the change in drug concentration over time for a specific population. The populations in population PK modelling often refer to subjects in a clinical trial of a potential drug candidate. Population PK models are frequently described by non-linear mixed effect (NLME) models, that including both random and fixed effect components. The fixed effect components

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