Sökning: "Alternative splicing"

Visar resultat 1 - 5 av 21 uppsatser innehållade orden Alternative splicing.

  1. 1. The effect of TRAP150 on HPV16 E1 gene regulation

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Emma Svanberg Frisinger; [2023]
    Nyckelord :;

    Sammanfattning : Human papilloma virus (HPV) is a small DNA virus that is known as the causative agent in cervical cancer. The virus is found worldwide and causes more than 300 000 deaths yearly. Although there are many types of HPV, HPV16 is found in 99 % of cervical cancer cases. LÄS MER

  3. 2. Differential expression and function of fubl-1 gene isoforms in C. elegans

    Kandidat-uppsats, Uppsala universitet/Molekylärbiologi; Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Joel Pålsson; [2022]
    Nyckelord :isoform; gene expression; C elegans; protein; alternative splicing; isoformer; genuttryck; C elegans; protein; alternativ splicing;

    Sammanfattning : Alternative splicing is the process of producing a variety of transcripts from one and the same gene. This adds further possible variability to gene expression and can in theory mean that one protein coding gene can produce multiple proteins with potentially different functions. LÄS MER

  4. 3. Alternativ Splicing som biomarkör vid systemisk lupus erythematosus

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Lina Rehnman; [2022]
    Nyckelord :systemisk lupus erythematosus; SLE; alternativ splicing; transkription;

    Sammanfattning : Characteristics as unknown cause, complicated pathophysiology and a great amount of complexity are describing systemic lupus erythematosus (SLE) more than well. It’s an autoimmune disease that is almost exclusive for women in their reproductive years and are believed to correlate with both genetics and environmental factors. LÄS MER

  5. 4. Systems biology of deregulated splicing in cancer. A pan-cancer analysis of dysfunctional splicing machinery and alternative splicing events.

    H-uppsats,

    Författare :Leticia Castillon; [2021-08-06]
    Nyckelord :multi-omics; splicing; alternative splicing; deep learning; cancer; transcriptome;

    Sammanfattning : The deregulation or disruption of the splicing process has been shown to play a role in the onset, development, and even response to treatment of some malignancies. Partly due to our incomplete understanding of the mechanism and regulation behind splicing and alternative splicing, the importance of aberrant splicing in oncogenesis is not yet understood. LÄS MER

  7. 5. Isoform 2 of DLG2 gene as a possible candidate tumour suppressor of neuroblastoma

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Paula Camargo Romera; [2021]
    Nyckelord :;

    Sammanfattning : Neuroblastoma (NB) is the most frequent extracranial solid tumour in childhood. The clinical diagnosis of NB is difficult due to the age of the patient and the vague appearance of the symptoms. Moreover, there are two groups of aggressive NBs, one with MYCN amplification and the other with an 11q deletion. LÄS MER