Sökning: "Amyloid fibril formation"

Hittade 3 uppsatser innehållade orden Amyloid fibril formation.

1. 1. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

   Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

   Författare :Josef Getachew; [2023]
   Nyckelord :α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

   Sammanfattning : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. LÄS MER

3. 2. Bri2 BRICHOS domain : Eukaryotic expression and importance of strictly conserved cysteine residues

   Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

   Författare :Lovisa Hemmingsson; [2017]
   Nyckelord :Bri2 BRICHOS; Aß; Chaperone; Amyloid fibril formation; Alzheimer disease; Eukaryotic expression; Cysteine residues;

   Sammanfattning : Alzheimer’s disease (AD), the most common form of dementia is associated with fibril formation of amyloid-ß peptides (Aß). Aß, proteolytically derived from Aß precursor protein (AßPP), is the major component of amyloid plaques in AD brains. LÄS MER

4. 3. Enhanced amyloid fibril formation of insulin in contact with catalytic hydrophobic surfaces

   Kandidat-uppsats, Institutionen för fysik, kemi och biologi

   Författare :Belma Salagic; [2007]
   Nyckelord :amyloid fibril formation of insulin; enhanced fibril formation of insulin;

   Sammanfattning : The important protein hormone insulin, responsible for different kind of functions in our body but mainly storage of nutrients, has for a long time been used for treatment of diabetic patients. This important protein is both physically and chemically unstable. LÄS MER