Sökning: "Cosmas Adindu Uzowuru"

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  1. 1. Inflammasome : Investigating the effect of NEK7 in the activation of the NLRP3 Inflammasome

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Cosmas Adindu Uzowuru; [2020]
    Nyckelord :NLRP3 inflammasome; NEK7 protein; THP-1; Prime; activate; differentiate; stimulate; cytokines; Interleukin-1 Beta; Interleukin-18;

    Sammanfattning : Inflammation is a biological defence mechanism applied by living organisms against foreign invaders. In the response to DAMPs and PAMPs, organisms use inflammatory multi-protein complexes to fight the attackers. The most studied inflammasome proteins are NLRP3, ASC and Caspase-1. LÄS MER