Sökning: "EF-hand"
Hittade 3 uppsatser innehållade ordet EF-hand.
1. Characterization of novel ZCa-based variants to investigate calcium dependent target interaction
Master-uppsats, KTH/ProteinvetenskapSammanfattning : ZCa is an engineered three-helical affinity protein that through replacement of the loop between helix two and three with an EF-hand motif has a calcium-dependent binding to its target. By using the difference of calcium concentration in the plasma and the cell along with the favorable properties of ZCa, the interest in creating therapeutics toward different diseases based on the ZCa scaffold has come about. LÄS MER
2. Towards Ca2+ Responsive Reticular Materials. An Evaluation of Suitable Conditions for Self-Assembly of the Protein S100G
Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemiSammanfattning : Att bygga material av proteiner är en konst som våra kroppar är specialister på. Men när vi medvetet försöker designa proteinmaterial, så blir det tydligt hur komplexa och svårstyrda biofysikens lagar är. LÄS MER
3. Method Development for Determining the Stability of Heat Stable Proteins Combined with Biophysical Characterization of Human Calmodulin and the Disease Associated Variant D130G
Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologiSammanfattning : Calmodulin is a highly conserved calcium ion binding protein expressed in all eukaryotic species. The 149 amino acid residues in the primary structure are organized in seven α helices with the highly flexible central α helix connecting the two non-cooperative domains of calmodulin. LÄS MER