Sökning: "Peptide characterization"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden Peptide characterization.

  1. 1. Expression optimization in Pichia pastoris with Signal Peptide Shuffling and characterization of putative oxygenases and glucose oxidase

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Anna Wolters; [2024]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 2. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS

    Master-uppsats, Lunds universitet/Centrum för analys och syntes

    Författare :Sara Forsberg; [2023]
    Nyckelord :High-throughput analysis; Impurity profiling; UHPLC-HRMS; Peptide characterization; Peptide descriptors; Analytical chemistry; Technology and Engineering;

    Sammanfattning : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. LÄS MER

  4. 3. Formulation and characterization of lipid-based nanocarriers for the delivery of antimicrobial peptide

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Srijani Saha; [2022]
    Nyckelord :AP114; Antimicrobial peptide AMP ; Nanostructured lipid carriers NLC ; Liposomes; Dynamic light scattering DLS ; Hydrodynamic size distribution; Zeta potential; Entrapment efficiency EE ; Release study;

    Sammanfattning : Bakterier som är resistenta mot antibiotika har de senaste åren blivit ett stort hot mot mänskligheten. Att utveckla nya antibiotikaläkemedel är väldigt tidskrävande samt kommer med en dyr prislapp. LÄS MER

  5. 4. Production and Evaluation of a Bombesin Analogue Conjugated to the Albumin-Binding Domain and DOTA for Prostate Cancer Radiotherapy

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Fredrika Landmark; [2021]
    Nyckelord :bombesin; prostate cancer; radiotherapy; human serum albumin; half-life extension; bombesin; prostatacancer; radioterapi; humant serumalbumin; halveringstidsförlängning;

    Sammanfattning : Prostate cancer is one of the most common types of cancer worldwide and claims hundreds of thousands of lives annually. Currently the most common treatment for prostate cancer is external beam radiotherapy, however, this treatment comes with serious side effects since it lacks selectivity for the cancer cells. LÄS MER

  7. 5. Biophysical characterization of and screening for binders and potentiator compounds that modulate the binding of PDZ domains to the C-terminal peptide motifs of target proteins

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Carl Olsson; [2021]
    Nyckelord :Post synaptic density protein 95; PDZ-domains; N-methyl-D-aspartate receptor; NMDAR hypofunctional hypothesis; GluN2b; Differential scanning fluorimetry; Surface plasmon resonance; Fragment based drug design; Assay development;

    Sammanfattning : The N-methyl-D-aspartate receptor (NMDAR) hypofunctional hypothesis is believed to explain one of the contributing factors to schizophrenia. This hypothesis suggests the dysregulation of NMDAR, a protein responsible for receiving signals from the synapses between neurons, is the cause of some of the symptoms seen in schizophrenia. LÄS MER