Sökning: "Wnt pathway."
Visar resultat 1 - 5 av 7 uppsatser innehållade orden Wnt pathway..
1. Actin filaments as an indicator of impaired neuronal differentiation mediated by disruption of the retinoic acid signalling pathway
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Retinoic acid (RA) is a well-known neurodevelopmental signaling molecule. It is reported to induce effects on neurite formation in differentiating neurons and to interfere with the actin cytoskeleton. Therefore, this project aimed to investigate the mechanisms behind effects of RA on the actin cytoskeleton of developing neurons using the C17. LÄS MER
2. The effect of DLG knockout, vitamin D and probiotic treatment on Drosophila gene expression
Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsa och lärandeSammanfattning : Background: Colorectal cancer is one of the most frequently diagnosed cancers today. Dlg is a tumor suppressor gene commonly silenced in cancer cells. Many colorectal cancer patients are subject to vitamin D3 deficiency and/ or an altered microbiome. LÄS MER
3. Novel target genes of ZEB1 and Snail1 in triple-negative human breast cancer.
Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologiSammanfattning : Breast cancer is comprised of several subtypes that are different from one another and thedivergence leads to different outcomes of the disease. There are known prognostic factors andphenotypic distinction in different biological factors and expression patterns, such as theestrogen receptor (ER), progesterone receptor (PR), Ki67, HER2/neu expression (HER2). LÄS MER
4. Role of Aurora kinase in Medulloblastoma development with correlation to MYCN activity
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Brain tumors are abnormal tissue masses found, either malignant or benign in nature. Medulloblastoma is a brain tumor subtype found to arise in the hind region of the brain, which is highly malignant and has poor long term prospects in general. LÄS MER
5. Prognostisk signifikans av SATB1 och SATB2 uttryck i kolorektal cancer
Uppsats för yrkesexamina på grundnivå, Malmö högskola/Fakulteten för hälsa och samhälle (HS)Sammanfattning : Kolorektal cancer (CRC) är en av de vanligaste cancersjukdomarna i världen med cirka 1 miljon nya detekterade fall per år. Special AT-rich sequence-binding protein1 (SATB1) är ett celltyp-specifikt kärnmatrix-associerat DNA-bindande protein, vilket utgörs av AT-rika DNA sekvenser. LÄS MER