Sökning: "cell heterogeneity"

Visar resultat 26 - 28 av 28 uppsatser innehållade orden cell heterogeneity.

  1. 26. Genetic heterogeneity of EGFR and KRAS mutations in primary tumor tissue from non-small cell lung cancer patients

    Magister-uppsats, Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Johanna Mattsson; [2011]
    Nyckelord :Non-small cell lung cancer; KRAS; EGFR; heterogeneity; mutation;

    Sammanfattning : Activated epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations characterize molecular subgroups of non-small cell lung cancer (NSCLC) and have a strong predictive value for response to EGFR inhibitor therapy. Recently, EGFR mutation testing was included in the diagnostic algorithm of NSCLC. LÄS MER

  3. 27. Breast cancer stem cells : evidence and contradictory views

    Kandidat-uppsats, SLU/Dept. of Anatomy, Physiology and Biochemistry

    Författare :Erica Rydhed; [2011]
    Nyckelord :breast cancer; stem cell; cancer stem cell theory; tumor initiating cell; origin;

    Sammanfattning : This literature study aims to examine the existence of cancer stem cells in breast cancer. The cancer stem cell theory states that there is a hierarchical organization within a tumour, in which a small subpopulation of the cells can initiate new tumours and maintain tumour growth whilst the bulk of the tumour cannot. LÄS MER

  4. 28. Microwell-based Collagen Matrix Migration Assays for NK:target Cell Interactions : Three-dimensional Imaging and Analysis of Transient Migration Behavior of NK Cells in vitro

    Master-uppsats, KTH/Cellens fysik

    Författare :Per Olofsson; [2011]
    Nyckelord :;

    Sammanfattning : Natural killer (NK) cells are lymphocytes of the innate immune system responsible for lysing tumor and virally-infected cells. Investigating NK cell heterogeneity can inform the development of more efficacious immunotherapeutic treatments. Cell motility is an essential aspect of NK cell function. LÄS MER