Sökning: "kinetic expression"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden kinetic expression.

1. 1. Development of osmo- and appetite regulation during transfer of smolt from freshwater to increasing salinities

   Master-uppsats, Göteborgs universitet / Institutionen för biologi och miljövetenskap

   Författare :Jonna Hellesten; [2023-01-26]
   Nyckelord :;

   Sammanfattning : Atlantic salmon (Salmo salar) is common in Scandinavian aquaculture and must be transferred from freshwater to seawater to grow properly. Despite being assessed as ready smolts, meaning they have gone through the physiological changes to prepare for SW transfer, the transfer result in a mortality rate of around 13-19%, and significant appetite- and growth reductions. LÄS MER

3. 2. Models for predicting efflux transport over the blood-brain barrier

   Master-uppsats, Uppsala universitet/Institutionen för farmaci

   Författare :Marjaneh Janani; [2020]
   Nyckelord :efflux transport; brain; blood-brain-barrier; Verapamil; Risperidone; Prazosin;

   Sammanfattning : Aim: The general aim of this research is development and evaluation of novel methods for predicting active transport over the human blood-brain-barrier (BBB), while this project specifically aims to i) review the literature and select suitable methods and substrates, ii) develop models for determining in vitro kinetic properties of selected compounds, analyze the in vitro data using the developed models and to use Maximum Transport Activity (MTA) approach (Karlgren et al., 2012), iii) perform Physiology Based Pharmacokinetic (PBPK) modelling and compare to in vivo literature data. LÄS MER

4. 3. Models for predicting efflux transport over the blood-brain barrier

   Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Marjaneh Janani; [2020]
   Nyckelord :Efflux; blood-brain-barrier; modeling; transporter;

   Sammanfattning : Aim: The general aim of this research is development and evaluation of novel methods for predicting active transport over the human blood-brain-barrier (BBB), while this project specifically aims to i) review the literature and select suitable methods and substrates, ii) develop models for determining in vitro kinetic properties of selected compounds, analyze the in vitro data using the developed models and to use Maximum Transport Activity (MTA) approach (Karlgren et al., 2012), iii) perform Physiology Based Pharmacokinetic (PBPK) modelling and compare to in vivo literature data. LÄS MER

5. 4. Conservation laws in kinetic theory for spin-1/2 particles

   Magister-uppsats, Umeå universitet/Institutionen för fysik

   Författare :Linnéa Gräns Samuelsson; [2015]
   Nyckelord :plasma; quantum mechanics; conservation; momentum; angular momentum; quantum plasma; kinetic theory; spin;

   Sammanfattning : In this thesis a kinetic theory for spin-1/2 particles is given a brief overview, focusing on the derivation of an evolution equation for the quasiprobability distribution function used in the theory to describe certain types of quantum plasma. The current theory is expanded upon by exploring conservation laws. LÄS MER

7. 5. Cloning, Expression and Purification of a Mutant Tomato Thymidine Kinase 1 for Crystallography

   Master-uppsats, Lunds universitet/Tillämpad biokemi

   Författare :Mohamad Nesrini; [2015]
   Nyckelord :protein expression; protein engineering; Azidothymidine; thymidine kinase; deoxyribonucleoside kinases; nucleosides; nucleoside analog; suicide gene therapy; tillämpad biokemi; applied biochemistry; BEVS.; Technology and Engineering; Chemistry;

   Sammanfattning : Thymidine kinase 1 from tomato (ToTK1) is a newly discovered deoxyribonucleoside kinase (dNK) that has been subject to study due to its in vitro and in vivo properties making it an interesting suicide gene candidate for the treatment of brain tumors. The ToTK1 phosphorylates the nucleoside analogue 3-azido-2,3-dideoxythymidine (azidothymidine, AZT) equally well as its natural substrate thymidine (dThd). LÄS MER