Sökning: "mRNA Sirt1"

Hittade 1 uppsats innehållade orden mRNA Sirt1.

  1. 1. Structural elucidation of mRNA(Sirt1)-microRNA 34a complex

    Master-uppsats, KTH/Skolan för teknikvetenskaplig kommunikation och lärande (ECE)

    Författare :Mona Farshchian; [2015]
    Nyckelord :mRNA Sirt1 ; miR-34a; in vitro transcription; gel electrophoresis; CD spectroscopy; NMR; cancer regulation via p53; HPLC; mRNA Sirt1 ; miR-34a; in vitro transkription; gel elektroforesis; CD spektroskopi; NMR; cancer regulering via p53; HPLC;

    Sammanfattning : The aim of this thesis is to understand RNA-RNA interactions steering cellular functions, as in the case of this thesis the structure of mRNA(Sirt1) in complex with microRNA-34a (miR-34a). MiR-34a regulates the cancer protein p53 via Sirt1 modulation. LÄS MER