Sökning: "macrophages"

Visar resultat 21 - 25 av 81 uppsatser innehållade ordet macrophages.

1. 21. Variations in the CCR5-gene and its effect on CAE, in goat

   Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

   Författare :Hanna Tiilikainen; [2021]
   Nyckelord :CCR5; caprine arthritis encephalitis; goat; SRLV; small ruminant lentiviruses;

   Sammanfattning : Caprine Arthritis Encephalitis (CAE) is a disease negatively affecting goats, around the world. A mutation on the CCR5-gene has showed an increase in viral load. CAE is a lentivirus that affects the monocytes/macrophages. It is a disease similar to HIV in humans and the animal can be a carrier for months to years before symptoms start to show. LÄS MER

3. 22. Possible interaction of sympathetic nerves with macrophages via fractalkine-CX3CR1 ligation in pancreatic islets

   Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Yuexi Wang; [2021]
   Nyckelord :;

   Sammanfattning : Disturbing the interaction between sympathetic nerves and macrophages in islets has been shown to protect from insulitis development. To study the intra-islet neuroimmune communications, we explored the interactions between macrophages and nerves in the islets by looking at their juxta-positioning in the islets of wild type and CX3CR1 knock out mice. LÄS MER

4. 23. Upregulation of CLIC1 gene in THP1 cells stimulated by lipopolysaccharides

   Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Karldiony Roskvist; [2021]
   Nyckelord :;

   Sammanfattning : The NLRP3 inflammasome is a multiprotein complex that controls caspase-1 activation and the development of the pro-inflammatory cytokines IL-1 and IL-18, as well as pyroptosis. The NLRP3 inflammasome in murine macrophages is normally triggered by pathogen-associated molecular patterns as well as a variety of structurally unrelated stimuli. LÄS MER

5. 24. The effect of deactivation or silencing of tumor stroma with angiogenesis inhibitor on malignancy of tumor metastases

   Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Nataly Tachijian; [2021]
   Nyckelord :neuroblastoma; SU11248; angiogenesis; tumor-associated macrophages; immunohistochemistry;

   Sammanfattning : Background: Neuroblastoma (NB) is a pediatric tumor in infants and young children. The survival rate is only around 50 percent for high-risk NB despite advanced and intense multi-modal therapy. Current research aims to find new effective treatment additional to modern therapy to improve prognosis of high-risk NB in children. LÄS MER

7. 25. Interactions between Rho-ROCK signaling and the tumor microenvironment in neuroblastoma

   Master-uppsats, Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Adena Pepich; [2021]
   Nyckelord :cancer and oncology; pediatric cancer; neuroblastoma; rho ROCK signaling; rho-associated kinases; tumor microenvironment; cytotoxic T cells; neuroblastom; pediatrik onkologi; rho-kinaser;

   Sammanfattning : Neuroblastoma is a childhood cancer of the peripheral sympathetic nervous system, emerging from cells of the neural crest. In Sweden, neuroblastoma accounts for 20 cases out of all, 300-350, pediatric cancer cases each year (Barncancerfonden 2019, Turup on behalf of Cancer Centrum 2019). LÄS MER