Sökning: "macrophages"

Visar resultat 6 - 10 av 81 uppsatser innehållade ordet macrophages.

  1. 6. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Alicia Bodin; [2023]
    Nyckelord :estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

    Sammanfattning : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. LÄS MER

  2. 7. Characterization of the immunomicroenvironment of glioblastoma : Optimization of an antibody panel for detection of glioblastoma TME cells and effect of C3 on glioma cells.

    Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Författare :Julia Wahldén; [2023]
    Nyckelord :Brain; cancer; glioblastoma; immune cells; immunofluorescence; tumor microenvironment; Cancer; glioblastom; immunceller; immunofluorescens; hjärnan; tumörmikromiljö;

    Sammanfattning : Glioblastoma (GBM) is the most common primary brain tumor in adults and represents one of the most aggressive tumor types. Despite treatment GBM remains incurable and when treated the tumor recurs more aggressive and treatment resistant than before. LÄS MER

  3. 8. Influence of Nrf2 Activators and Keap1 Inhibitors on Antioxidative Phenotypes of THP-1-Derived M1 and M2 macrophages: Therapeutic Potential for Systemic Lupus Erythematosus

    Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Leo Svahn; [2023]
    Nyckelord :NRF2; KEAP1; THP-1; M1; M2; SLE;

    Sammanfattning : POPULAR SCIENTIFIC SUMMARY Systemic lupus erythematosus (SLE) is not your average disorder. It behaves like a mischievous troublemaker, wreaking havoc throughout the body, causing inflammation that affects multiple organs. LÄS MER

  4. 9. Inflammatory Cell Infiltration and Expression of AT1 and AT2 Receptors in Angiotensin II and High-Salt Diet-Induced Balb/CJ Mice

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk cellbiologi

    Författare :Avishka Herat; [2023]
    Nyckelord :;

    Sammanfattning : Pulmonary oedema and pulmonary hypertension are often associated with heart failure. The Balb/CJ and C57BL/6J mouse strains have been shown to exhibit distinct genetic susceptibilities to heart failure. LÄS MER

  5. 10. Digital Image Analysis using Qupath to determine immune cell content in formalin-fixed, paraffin-embedded murine neuroblastoma tumors

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Anton Bergström Holm; [2023]
    Nyckelord :Neuroblastoma; Tumor-associated neutrophils TANs ; Digital image analysis; QuPath;

    Sammanfattning : Neuroblastoma (NB), an extracranical solid tumor, is among the most prevalent cancers affecting children, particularly those under the age of five. High-risk NB presents a survival rate just below 50 %. Angiogenesis, a crucial process in NB, is induced by various pro-angiogenic factors. LÄS MER