Sökning: "rho ROCK signaling"

Hittade 2 uppsatser innehållade orden rho ROCK signaling.

  1. 1. Interactions between Rho-ROCK signaling and the tumor microenvironment in neuroblastoma

    Master-uppsats, Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Adena Pepich; [2021]
    Nyckelord :cancer and oncology; pediatric cancer; neuroblastoma; rho ROCK signaling; rho-associated kinases; tumor microenvironment; cytotoxic T cells; neuroblastom; pediatrik onkologi; rho-kinaser;

    Sammanfattning : Neuroblastoma is a childhood cancer of the peripheral sympathetic nervous system, emerging from cells of the neural crest. In Sweden, neuroblastoma accounts for 20 cases out of all, 300-350, pediatric cancer cases each year (Barncancerfonden 2019, Turup on behalf of Cancer Centrum 2019). LÄS MER

  2. 2. Human platelet aggregation induced via protease-activated receptor 1 (PAR1)signaling is reversed by nitric oxide (NO) through inhibition of a Rho-kinase/ROCK-mediated pathway

    Master-uppsats, Institutionen för fysik, kemi och biologi

    Författare :Patrik Björn; [2010]
    Nyckelord :Platelet; nitric oxide; PAR1; Rho-kinase; ROCK;

    Sammanfattning : Human platelets are constantly regulated by activating and inhibitory effectors. Thrombin,the most potent platelet agonist, induces signaling through the protease-activated receptors(PARs) 1 and 4 which in turn convey their signal by coupling to G-proteins. LÄS MER