Sökning: "spps"

Visar resultat 1 - 5 av 18 uppsatser innehållade ordet spps.

  1. 1. Greening peptide chemistry by using NBP as solvent for SPPS

    Master-uppsats, Lunds universitet/Centrum för analys och syntes

    Författare :Andrea Ölander; [2022]
    Nyckelord :SPPS; Green chemistry; Peptide Synthesis; Organic chemistry; Organisk kemi; Chemistry;

    Sammanfattning : The preferred method for synthesising therapeutic peptides today is by Solid-Phase Peptide Synthesis (SPPS). SPPS is a wasteful process, where the main component of the waste is hazardous solvents, i.e., N,N-dimethylformamide (DMF), N-methylpyrrolidone (NMP) or dichloromethane (DCM). LÄS MER

  3. 2. Streamlining the manufacturing of biotherapeutics : SPPS vs. Recombinant protein production

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Matilda Carlson; Alma Hansen; Tyra Levin; Moa Rick; Frida Tallqvist; Malin Tiefensee; [2021]
    Nyckelord :;

    Sammanfattning : In this paper we have researched two methods for peptide synthesis; solid phase peptide synthesis (SPPS) and recombinant protein production, hereafter called recombinant production. The goal was to create a decision support that can be of use when choosing a production method for a given peptide. LÄS MER

  4. 3. Production and Evaluation of a Bombesin Analogue Conjugated to the Albumin-Binding Domain and DOTA for Prostate Cancer Radiotherapy

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Fredrika Landmark; [2021]
    Nyckelord :bombesin; prostate cancer; radiotherapy; human serum albumin; half-life extension; bombesin; prostatacancer; radioterapi; humant serumalbumin; halveringstidsförlängning;

    Sammanfattning : Prostate cancer is one of the most common types of cancer worldwide and claims hundreds of thousands of lives annually. Currently the most common treatment for prostate cancer is external beam radiotherapy, however, this treatment comes with serious side effects since it lacks selectivity for the cancer cells. LÄS MER

  5. 4. Minimizing Liquid Waste in Peptide Synthesis : A New Application for the Rotating Bed Reactor

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Peter Nordström; [2021]
    Nyckelord :Chemical reactor; Rotating Bed Reactor; Solid-phase peptide synthesis; Peptide synthesis.;

    Sammanfattning : Peptide drugs are used to treat a broad spectrum of diseases such as cancer and HIV and have many more promising applications, such as new vaccines against SARS-CoV-2. The most popular manufacturing method for peptides is solid-phase peptide synthesis (SPPS). The main drawback of SPPS is that it is a costly and wasteful process. LÄS MER

  7. 5. Medietillit under pandemi : En kvantitativ studie i tillit till medierna under en pandemi

    M1-uppsats, Södertörns högskola/Medie- och kommunikationsvetenskap

    Författare :Axel Reinholdt; [2020]
    Nyckelord :Covid-19; Medietillit; Pandemi; Kriskommunikation; Sverige; tillit;

    Sammanfattning : Avsikten med denna uppsats är att belysa hur tilliten till medier och dess rapportering under en kris som t.ex. en pandemi ser ut. Den så kallade Covid-19 pandemin tog sin början i januari 2020 och är fortfarande – i april 2021 – i full gång över hela världen. LÄS MER